//podcastplus.net/feed/talking-techniques~e5342b78 Welcome to Talking Techniques! In this Podcast BioTechniques Digital Editor Tristan Free, interviews researchers at the forefront of their fields about the latest breakthroughs, controversies and conversations in the life sciences. From CRISPR to COVID-19, organoids to the microbiome, this podcast will explore the latest developments in the lab and interesting applications of techniques, while trying to determine how we can drive science forward in progressive and inventive ways. Hosted on Acast. See acast.com/privacy for more information. Thu, 13 Aug 2026 21:07:40 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/6842f03dc4b70577af932a35/media.mp3 In this episode of Talking Techniques, Ritwika Biswas, Field Application Scientist at Sino Biological US Inc. (PA, USA), discusses the role of cytokines in autoimmune diseases, the techniques used to examine them and some emerging therapeutic innovations beginning to change the way we approach the treatment of autoimmune diseases. Contents Introduction: 00:00–02:06 The role of cytokines in a healthy body: 02:06–03:57 Cytokines in autoimmune diseases: 03:57–06:24 Techniques for detecting cytokines in autoimmune diseases: 06:24–09:48 Targeting cytokines for therapeutic purposes: 09:48–11:54 Challenges with targeting cytokines in autoimmune diseases: 11:54–14:28 Addressing the challenges of targeting cytokines: 14:28–16:43 Established cytokine-targeting drugs: 16:43–18:57 The future of cytokines in autoimmune diseases: 18:57–21:54   Hosted on Acast. See acast.com/privacy for more information. Thu, 19 Jun 2025 08:41:12 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/6842f03dc4b70577af932a35/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/6842f03dc4b70577af932a35/media.mp3 In this episode of Talking Techniques, Ritwika Biswas, Field Application Scientist at Sino Biological US Inc. (PA, USA), discusses the role of cytokines in autoimmune diseases, the techniques used to examine them and some emerging therapeutic innovations beginning to change the way we approach the treatment of autoimmune diseases. Contents Introduction: 00:00–02:06 The role of cytokines in a healthy body: 02:06–03:57 Cytokines in autoimmune diseases: 03:57–06:24 Techniques for detecting cytokines in autoimmune diseases: 06:24–09:48 Targeting cytokines for therapeutic purposes: 09:48–11:54 Challenges with targeting cytokines in autoimmune diseases: 11:54–14:28 Addressing the challenges of targeting cytokines: 14:28–16:43 Established cytokine-targeting drugs: 16:43–18:57 The future of cytokines in autoimmune diseases: 18:57–21:54   Hosted on Acast. See acast.com/privacy for more information. Thu, 19 Jun 2025 08:41:12 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/6842f03dc4b70577af932a35/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66c4c8664bc29b3432fa18fd/media.mp3 This episode of Talking Technique deviates slightly from specific lab technologies to instead discuss techniques and methods we use for teaching and testing life sciences. To do this, I’m speaking to two pioneers of unconventional teaching and testing approaches to STEM education. Angela Consani is the Co-Founder and CEO of the Bioscience Core Skills Institute (KS, USA). This skills-first microcredential program provides certification for lab skills in techniques, safety and quality control, using performance-based practical testing. Natalie Kuldell is the Founder and Executive Director of Biobuilder (MA, USA), a nonprofit organization, set up to increase interest, understanding and engagement in STEM by converting lab research projects in into teachable modules aimed primarily at the pre-graduate level to give students the practical skills needed for a career in the life sciences. Together, we’ll question the current system of STEM education and training and whether it captures ... Tue, 20 Aug 2024 16:46:30 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66c4c8664bc29b3432fa18fd/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66c4c8664bc29b3432fa18fd/media.mp3 This episode of Talking Technique deviates slightly from specific lab technologies to instead discuss techniques and methods we use for teaching and testing life sciences. To do this, I’m speaking to two pioneers of unconventional teaching and testing approaches to STEM education. Angela Consani is the Co-Founder and CEO of the Bioscience Core Skills Institute (KS, USA). This skills-first microcredential program provides certification for lab skills in techniques, safety and quality control, using performance-based practical testing. Natalie Kuldell is the Founder and Executive Director of Biobuilder (MA, USA), a nonprofit organization, set up to increase interest, understanding and engagement in STEM by converting lab research projects in into teachable modules aimed primarily at the pre-graduate level to give students the practical skills needed for a career in the life sciences. Together, we’ll question the current system of STEM education and training and whether it captures ... Tue, 20 Aug 2024 16:46:30 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66c4c8664bc29b3432fa18fd/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66914a580931c691503d8d96/media.mp3 This episode of the Talking Techniques podcast dives into the realm of cancer immunotherapies, focusing on antigen discovery and T-cell receptor engineering for T-cell therapies. Guiding us through the field is Jim Heath, President of the Institute for Systems Biology in Seattle, where he runs the Heath Lab, investigating fundamental immunology, and infectious and chronic diseases. Jim discusses the computational models and wet lab techniques he uses to characterize T cells, the importance of targeting a balanced immune response with immunotherapies and more in this podcast recorded at AACR 2024 (5th–10th April 2024; San Diego, CA, USA). Contents: Introductions: 00:00-02:00 Intro to cancer vaccines and T-cell therapies: 02:00-04:00 Antigen detection and validation in T-cell therapies: 04:00-05:20 Wet lab and computational techniques for antigen detection: 05:20-09:15 The importance of a balanced immune response to cancer immunotherapies: 09:15-10:30 Technological developments in antig... Fri, 12 Jul 2024 15:23:03 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66914a580931c691503d8d96/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66914a580931c691503d8d96/media.mp3 This episode of the Talking Techniques podcast dives into the realm of cancer immunotherapies, focusing on antigen discovery and T-cell receptor engineering for T-cell therapies. Guiding us through the field is Jim Heath, President of the Institute for Systems Biology in Seattle, where he runs the Heath Lab, investigating fundamental immunology, and infectious and chronic diseases. Jim discusses the computational models and wet lab techniques he uses to characterize T cells, the importance of targeting a balanced immune response with immunotherapies and more in this podcast recorded at AACR 2024 (5th–10th April 2024; San Diego, CA, USA). Contents: Introductions: 00:00-02:00 Intro to cancer vaccines and T-cell therapies: 02:00-04:00 Antigen detection and validation in T-cell therapies: 04:00-05:20 Wet lab and computational techniques for antigen detection: 05:20-09:15 The importance of a balanced immune response to cancer immunotherapies: 09:15-10:30 Technological developments in antig... Fri, 12 Jul 2024 15:23:03 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/66914a580931c691503d8d96/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/668eb13e50adcd2e71a7b9f5/media.mp3 In this episode of Talking Techniques, Ritwika Biswas, Field Application Scientist at Sino Biological US Inc. (PA, USA), discusses the use of cytokines in immunotherapy. Ritwika details the role of cytokines in the body, before going on to discuss how they can be used as therapeutics and to guide treatment decisions. Ritwika also shares how she thinks these proteins will be used in the future. Contents ·      Introduction: 00:00–01:35 ·      The role of cytokines in the body: 01:35–02:52 ·      Immune regulation and signaling: 02:52–05:40 ·      Cytokine interactions and networks: 05:40–08:42 ·      Modulating cytokine activity for therapeutic purposes: 08:42–12:35 ·    &amp... Wed, 10 Jul 2024 16:07:02 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/668eb13e50adcd2e71a7b9f5/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/668eb13e50adcd2e71a7b9f5/media.mp3 In this episode of Talking Techniques, Ritwika Biswas, Field Application Scientist at Sino Biological US Inc. (PA, USA), discusses the use of cytokines in immunotherapy. Ritwika details the role of cytokines in the body, before going on to discuss how they can be used as therapeutics and to guide treatment decisions. Ritwika also shares how she thinks these proteins will be used in the future. Contents ·      Introduction: 00:00–01:35 ·      The role of cytokines in the body: 01:35–02:52 ·      Immune regulation and signaling: 02:52–05:40 ·      Cytokine interactions and networks: 05:40–08:42 ·      Modulating cytokine activity for therapeutic purposes: 08:42–12:35 ·    &amp... Wed, 10 Jul 2024 16:07:02 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/668eb13e50adcd2e71a7b9f5/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/65e85ce6b75ceb0016bd2f70/media.mp3 The cell-surface proteome plays a critical role in immune-cell function; however, our ability to examine its interactions and spatial organization has previously been limited by available proteomic techniques. This episode explores the function of immune-cell membrane proteins and how the latest developments in spatial proteomics have enabled more detailed interrogation of these proteins and their spatial relationships. Our guest, Hanna van Ooijen, Immunology Application Scientist at Pixelgen Technologies guides us through the field, revealing a new technique that enables spatial analysis of the cell-surface proteome at a single-cell resolution and highlighting some exciting discoveries that it has facilitated. Contents: Introductions: 00:00-01:40 Introducing Molecular Pixelation: 01:40-02:15 Example applications of Molecular Pixelation: 02:15-03:20 The role of membrane proteins in immune cell function: 03:20-07:25 Traditional techniques to investigate cell membrane proteins: 07:15-10:20 ... Fri, 22 Mar 2024 14:21:52 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/65e85ce6b75ceb0016bd2f70/media.mp3 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/65e85ce6b75ceb0016bd2f70/media.mp3 The cell-surface proteome plays a critical role in immune-cell function; however, our ability to examine its interactions and spatial organization has previously been limited by available proteomic techniques. This episode explores the function of immune-cell membrane proteins and how the latest developments in spatial proteomics have enabled more detailed interrogation of these proteins and their spatial relationships. Our guest, Hanna van Ooijen, Immunology Application Scientist at Pixelgen Technologies guides us through the field, revealing a new technique that enables spatial analysis of the cell-surface proteome at a single-cell resolution and highlighting some exciting discoveries that it has facilitated. Contents: Introductions: 00:00-01:40 Introducing Molecular Pixelation: 01:40-02:15 Example applications of Molecular Pixelation: 02:15-03:20 The role of membrane proteins in immune cell function: 03:20-07:25 Traditional techniques to investigate cell membrane proteins: 07:15-10:20 ... Fri, 22 Mar 2024 14:21:52 +0000 https://sphinx.acast.com/p/open/s/5f2442bc6de29f32c4d05451/e/65e85ce6b75ceb0016bd2f70/media.mp3