//podcastplus.net/feed/drugbytes~1bbbcdac DrugBytes is the new pharmacology podcast by MedTutes! Each 15-20min episode will cover the key clinical points important to med students on a high yield drug class, including the basic mechanism of action, common examples in each class, and a few points on pharmacokinetics. Each episode is also accompanied by a one-page summary of show notes, which you can download for free on the MedTutes website - www.medtutes.wordpress.com Mon, 20 Apr 2026 09:04:57 +0000 https://www.buzzsprout.com/865309/3206233-diuretics.mp3 In this episode we review the basics of renal physiology in order to discuss the four classes of diuretics: Loop diuretics Thiazide diuretics Potassium sparing diuretics Osmotic diuretics Tune in to hear how these drugs work, and how we manage their side effects! You can access the show notes at  https://medtutes.wordpress.com/podcasts/ Follow us on Facebook, Twitter, Youtube and Reddit by searching "MedTutes". Wed, 01 Apr 2020 22:00:00 +0000 https://www.buzzsprout.com/865309/3206233-diuretics.mp3 https://www.buzzsprout.com/865309/3206233-diuretics.mp3?blob_id=11440543 In this episode we review the basics of renal physiology in order to discuss the four classes of diuretics: Loop diuretics Thiazide diuretics Potassium sparing diuretics Osmotic diuretics Tune in to hear how these drugs work, and how we manage their side effects! You can access the show notes at  https://medtutes.wordpress.com/podcasts/ Follow us on Facebook, Twitter, Youtube and Reddit by searching "MedTutes". Wed, 01 Apr 2020 22:00:00 +0000 https://www.buzzsprout.com/865309/3206233-diuretics.mp3?blob_id=11440543 https://www.buzzsprout.com/865309/3090079-special-episode-hydroxychloroquine-in-covid19.mp3 Things are moving quickly at the moment, and we already have an update to our previous special podcast on COVID19. This podcast clears up where we stand on ibuprofen in COVID19, but mainly focuses on hydroxychloroquine based on a paper released by Liu et al available at -          https://www.nature.com/articles/s41421-020-0156-0.pdf This podcast discusses some of the major side effects to be aware of when use hydroxychloroquine, as well as it's history and how the recent paper describes it may exert it's anti-SARS-CoV-2 effect. As always, the show notes are available at  https://medtutes.wordpress.com/podcasts/ Intro Music - Feelin' Good by Purple Planet Music Outro - Burn Me Down by Sekai courtesy of NCS Mon, 23 Mar 2020 03:00:00 +0000 https://www.buzzsprout.com/865309/3090079-special-episode-hydroxychloroquine-in-covid19.mp3 https://www.buzzsprout.com/865309/3090079-special-episode-hydroxychloroquine-in-covid19.mp3?blob_id=10901458 Things are moving quickly at the moment, and we already have an update to our previous special podcast on COVID19. This podcast clears up where we stand on ibuprofen in COVID19, but mainly focuses on hydroxychloroquine based on a paper released by Liu et al available at -          https://www.nature.com/articles/s41421-020-0156-0.pdf This podcast discusses some of the major side effects to be aware of when use hydroxychloroquine, as well as it's history and how the recent paper describes it may exert it's anti-SARS-CoV-2 effect. As always, the show notes are available at  https://medtutes.wordpress.com/podcasts/ Intro Music - Feelin' Good by Purple Planet Music Outro - Burn Me Down by Sekai courtesy of NCS Mon, 23 Mar 2020 03:00:00 +0000 https://www.buzzsprout.com/865309/3090079-special-episode-hydroxychloroquine-in-covid19.mp3?blob_id=10901458 https://www.buzzsprout.com/865309/3060664-special-episode-antivirals-in-covid19.mp3 In this special episode we provide a brief rundown of the current antiviral treatments being trialled in critically ill COVID19 patients. We look at some of the (very) recent studies as well as previous research conducted during the original SARS outbreak in 2002, which is definitely of relevance due to the similarities in the mechanisms of entry and replication of SARS-CoV-2 compared with SARS-CoV. I repeatedly talk about the Internet Book of Critical Care source in this podcast, you can access it here: https://emcrit.org/ibcc/COVID19/ They also have a podcast I would very highly recommend listening in to. Show notes for this episode are available at https://medtutes.wordpress.com/podcasts/ The notes for this episode also contain numerous sources to the papers referenced in this podcast. Like the podcast? Then connect with us on social media so you don't miss the next one! You can follow us on Facebook, Twitter, Youtube, or Reddit. Just search MedTutes. Intro - Feeling Good by Pur... Thu, 19 Mar 2020 22:00:00 +0000 https://www.buzzsprout.com/865309/3060664-special-episode-antivirals-in-covid19.mp3 https://www.buzzsprout.com/865309/3060664-special-episode-antivirals-in-covid19.mp3?blob_id=10765024 In this special episode we provide a brief rundown of the current antiviral treatments being trialled in critically ill COVID19 patients. We look at some of the (very) recent studies as well as previous research conducted during the original SARS outbreak in 2002, which is definitely of relevance due to the similarities in the mechanisms of entry and replication of SARS-CoV-2 compared with SARS-CoV. I repeatedly talk about the Internet Book of Critical Care source in this podcast, you can access it here: https://emcrit.org/ibcc/COVID19/ They also have a podcast I would very highly recommend listening in to. Show notes for this episode are available at https://medtutes.wordpress.com/podcasts/ The notes for this episode also contain numerous sources to the papers referenced in this podcast. Like the podcast? Then connect with us on social media so you don't miss the next one! You can follow us on Facebook, Twitter, Youtube, or Reddit. Just search MedTutes. Intro - Feeling Good by Purple Plane... Thu, 19 Mar 2020 22:00:00 +0000 https://www.buzzsprout.com/865309/3060664-special-episode-antivirals-in-covid19.mp3?blob_id=10765024 https://www.buzzsprout.com/865309/3010966-nsaids-and-aspirin.mp3?blob_id=10539625 In this episode we discuss the Arachidonic Acid pathway, and how steroids and more specifically non-steroidal anti-inflammatory drugs (NSAIDs) work to limit inflammation and pain. We also discuss the special effects of aspirin as an anti-platelet agent, and the only NSAID that decreases cardiovascular risk rather than increasing. Show notes are available at www.medtutes.wordpress.com or here, at https://drive.google.com/open?id=1Egw_tHcIBjSt45i-9HJ1WPzEpPxTqCd5 Get in touch! We're on Facebook, Twitter, YouTube and Reddit, and we'd love to hear from you! Sun, 15 Mar 2020 04:00:00 +0000 https://www.buzzsprout.com/865309/3010966-nsaids-and-aspirin.mp3?blob_id=10539625 https://www.buzzsprout.com/865309/3010966-nsaids-and-aspirin.mp3 In this episode we discuss the Arachidonic Acid pathway, and how steroids and more specifically non-steroidal anti-inflammatory drugs (NSAIDs) work to limit inflammation and pain. We also discuss the special effects of aspirin as an anti-platelet agent, and the only NSAID that decreases cardiovascular risk rather than increasing. Show notes are available at www.medtutes.wordpress.com or here, at https://drive.google.com/open?id=1Egw_tHcIBjSt45i-9HJ1WPzEpPxTqCd5 Get in touch! We're on Facebook, Twitter, YouTube and Reddit, and we'd love to hear from you! Sun, 15 Mar 2020 04:00:00 +0000 https://www.buzzsprout.com/865309/3010966-nsaids-and-aspirin.mp3 https://www.buzzsprout.com/865309/2836432-analgesia-opioids-and-the-who-pain-ladder.mp3?blob_id=9761902 Buckle up, this is a big one! (with a long intro, sorry about that). In this episode we scrape the surface on the complicated world of pain management. This podcast is just a brief overview, including paracetamol/acetaminophen, opioids, gabapentinoids, and adjuvants. This podcast is meant to complement further teaching on pain pathways/pathophysiology, pain management, and substance use disorders. The field is very complicated, and we can't cover it all in one podcast! This episode also links in to the next podcast in the series on NSAIDs and Aspirin. There were 3 things I forgot to elaborate on in the podcast whilst trying to keep it as short as possible 1. Morphine (and many other opioids) are renally cleared. In patient with poor renal function (eg. elderly with CKD, or people with AKI) morphine must be dose adjusted! Opioids are notorious for precipitating delirium in the elderly populations especially if they aren't dose adjusted, and this can also lead to overdose. 2. Gabapentinoids work throug... Tue, 25 Feb 2020 08:00:00 +0000 https://www.buzzsprout.com/865309/2836432-analgesia-opioids-and-the-who-pain-ladder.mp3?blob_id=9761902 https://www.buzzsprout.com/865309/2836432-analgesia-opioids-and-the-who-pain-ladder.mp3 Buckle up, this is a big one! (with a long intro, sorry about that). In this episode we scrape the surface on the complicated world of pain management. This podcast is just a brief overview, including paracetamol/acetaminophen, opioids, gabapentinoids, and adjuvants. This podcast is meant to complement further teaching on pain pathways/pathophysiology, pain management, and substance use disorders. The field is very complicated, and we can't cover it all in one podcast! This episode also links in to the next podcast in the series on NSAIDs and Aspirin. There were 3 things I forgot to elaborate on in the podcast whilst trying to keep it as short as possible 1. Morphine (and many other opioids) are renally cleared. In patient with poor renal function (eg. elderly with CKD, or people with AKI) morphine must be dose adjusted! Opioids are notorious for precipitating delirium in the elderly populations especially if they aren't dose adjusted, and this can also lead to overdose. 2. Gabapent... Tue, 25 Feb 2020 08:00:00 +0000 https://www.buzzsprout.com/865309/2836432-analgesia-opioids-and-the-who-pain-ladder.mp3